Discovery of drug candidate to potentially tackle ER-positive breast cancer
Credit score: Cell Chemical Biology (2023). DOI: 10.1016/j.chembiol.2023.07.005 A global staff of researchers, led by Pfizer in collaboration with Monash ...
Tag: drug
New neuromuscular model promises to revolutionize high-throughput drug screening studies
A human self-organizing 2D neuromuscular junction mannequin. Immunofluorescence evaluation of the entire dish reveals muscle cells (magenta) organized in bundles ...
Discovery unveils promising anticancer drug targeting KRAS protein
KRB-456 inhibits the expansion in vivo of orthotopic mt KRAS tumors derived from pancreatic most cancers sufferers. Tumor biopsies from ...
How research helped lead to FDA approval of a pediatric neuroblastoma drug
Credit score: Unsplash/CC0 Public Area In 2003, the primary 12 months of her fellowship in pediatric oncology, two of Giselle ...
Significant benefit seen in Phase III trial of experimental drug for kidney disease
Credit score: Pixabay/CC0 Public Area In a scientific trial of sufferers with persistent kidney illness, an experimental drug considerably diminished ...
New drug helps narrow racial survival disparity in patients with acute myeloid leukemia: Study
Bone marrow aspirate exhibiting acute myeloid leukemia. A number of blasts have Auer rods. Credit score: Wikipedia Non-Hispanic Black sufferers ...
New weight-loss drug Zepbound is now available, company says
The newly authorized weight-loss treatment often known as Zepbound is now obtainable for sufferers to take, drug maker Eli Lilly ...
Reprogramming drug resistance signals with an artificial gene circuit device
Vincristine monotherapy triggers NF-κB activation, inducing OIP5 expression linked to most cancers cell resistance in opposition to vincristine. The engineered ...
HIV drug could prevent coronaviruses, study finds
Structural comparability of cobicistat and ritonavir. The structural variations between the 2 medication (i.e., morpholine ring substitution in cobicistat and ...
Experimental drug combination shows promise against hard-to-treat peripheral nerve sheath tumors
Synthesis and characterization of Professional-905, a novel thioguanine protide with exercise in MPNST. A, Schematic of purine base salvage and ...