New treatment modality may reduce obesity in schizophrenia patients

In people with schizophrenia, accelerated steady theta burst stimulation (cTBS) appears promising for treating weight problems, based on a examine revealed on-line Oct. 31 in Schizophrenia Bulletin.

Dongyu Kang, M.D., from The Second Xiangya Hospital of Central South College in Changsha, China, and colleagues carried out a double-blind, randomized trial to look at the efficacy of noninvasive magnetic stimulation methods in decreasing weight problems amongst individuals with schizophrenia. Forty overweight individuals with schizophrenia had been recruited and randomly assigned to lively intervention, which included 50 accelerated cTBS periods over the left main motor space, or sham intervention.

The researchers discovered that the lively group had a big lower in physique weight and physique mass index after the intervention; this enchancment endured on the one-month follow-up. Within the lively group, the rating on the Barratt Impulsivity Scale decreased and mediated the impact of accelerated cTBS on body weight.

After the lively intervention, the late constructive potential part, which is expounded to motivated consideration and emotional processing, decreased in frontal mind areas and elevated in posterior areas within the meals image cue electroencephalograph job.

“The intervention was discovered to be related to decreased impulsivity and elevated motivated consideration allocation to food-related cues,” the authors write. “These findings are notably noteworthy, contemplating the extreme metabolic unwanted side effects related to many second-generation antipsychotics.”

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