Study reveals high accuracy of MR-guided radiotherapy for intracranial stereotactic radiosurgery

A new studyled by radiation oncology physicists at Miami Most cancers Institute, a part of Baptist Well being South Florida, has displayed constructive outcomes utilizing intracranial stereotactic radiosurgery, also called SRS, for an MR-guided radiotherapy system.

The research, “Commissioning Intracranial Stereotactic Radiosurgery (SRS) for an MR-guided Radiotherapy (MRgRT) system: MR-RT Localization and Dosimetric Finish-to-Finish Validation,” is revealed within the Worldwide Journal of Radiation Oncology—Biology—Physics (IJROBP). It highlights constructive accuracy by an end-to-end hidden goal take a look at to quantify the imaging, planning, and supply coincidence of an MR Linac system, ViewRay MRIdian.

Kathryn Mittauer, Ph.D., lead physicist for the MR-guided radiation remedy program with Miami Most cancers Institute, was the primary writer of this research. Mittauer explains that the workforce developed an in-house MR head phantom to simulate stereotactic radiosurgery for mind tumors. Particularly, the research simulated intracranial spherical targets, an irregularly formed goal, and a goal abutting brainstem.

Nema Bassiri, Ph.D., radiation oncology physicist with Miami Most cancers Institute, and senior writer of this research, explains that this supply was profitable with as much as 99% accuracy. Bassiri provides that “this work allows the utilization of novel MR-guided radiotherapy know-how for intracranial SRS, which has not been used with MR Linac methods.” MRI is the gold normal to guage and localize brain tumors resulting from gentle tissue visualization capabilities.

“Since we demonstrated the accuracy of ViewRay MRIdian’s functionality to ship inside a 1 mm setup margin on this work, we’ve got now deployed this novel method to our mind cancer sufferers at Miami Most cancers Institute,” provides Mittauer. The workforce has noticed that the quantity of a affected person’s tumor modified throughout a 3-fraction radiosurgery course by utilizing the onboard MR picture steerage of the MR Linac system.

“What’s most spectacular is that we’re in a position to visualize how the tumor quantity adjustments everyday, even all through a brief 3-fraction therapy. This analysis will assist us higher perceive how these tumors change (together with tumor development), and the function of adaptive radiotherapy which adjusts the radiation to account for these adjustments to allow extra precision,” shared Mittauer. “Within the discipline of radiation oncology, that is revolutionary as we assess the frequency of those anatomical adjustments and the way this may inform us for even different radiation decisions.”

“Sooner or later, we are going to see extra research that examine the advantage of utilizing MRIdian for stereotactic radiosurgery. This research will assist advance the group by offering a blueprint to implement MR-guided SRS program for anybody who’s enthusiastic about using this therapy method,” shared Bassiri.

Supplied by
Baptist Well being South Florida